Can we just say NO to sickle cell anemia?
نویسنده
چکیده
منابع مشابه
Side Effects of Hydroxyurea in Patients with Sickle Cell Anemia
Background: Hemoglobin S arises is the result of a point mutation (A-T) in the sixth codon on the -globin gene on chromosome 11 causing sickle cell anemia. The presence of fetal hemoglobin in infancy plays a relatively protective role for vaso-occlusive symptoms that are the major contributor for the morbidity and mortality among patients with sickle cell anemia. hydroxyurea, an s-phase-specif...
متن کاملEffect of Non- pharmacological Palliative Methods Training on Sickle Cell Anemia Outcomes
Background Drugs used by patients with sickle cell anemia to relieve pain have side effects, so the use of non-pharmacological palliative methods (such as massage, muscle relaxation, heat, drinking fluids, etc.) can be considered. We aimed to determine effect of non-pharmacological palliative methods training among adolescents with sickle cell anemia. <stro...
متن کاملThe Effect of L-Glutamine on Pain Crisis Reduction in Patients with Sickle Cell Anemia and Sickle β°-Thalassemia
Background: A low level of L-glutamine, a precursor of nicotinamide adenine dinucleotide (NAD) in red blood cells (RBCs), is identified as an underlying mechanism for the potential decrement of the NAD redox and the incidence of pain crisis in sickle cell anemia (SCA). The aim of this study is to assess the impact of oral L-glutamine therapy on pain crisis reduction in patients with SCA and sic...
متن کاملResults of Transcranial Doppler in Children with Sickle Cell Disease: Correlation between the Time-Averaged Mean of Maximum Velocity and Some Hematological Characteristics
Abstract Background: Transcranial Doppler ultrasonography results have not been previously studied in among Iranian sickle cell anemia patients. The present study was performed to evaluate the pattern of intracranial flow velocities among Iranian children with sickle cell anemia and the hematological parameters that can affect the time-averaged mean of maximum velocity in major intracranial...
متن کاملThe Influence of Fetal Hemoglobin on Clinical and Hematological Variables of Children and Adolescents with Sickle Cell Anemia in Basra, Southern Iraq
Background: There are many parameters that modulate the severity of sickle cell anemia. Fetal hemoglobin (Hb F) is one of these major variables. However, its effect is clinically inconsistent. We conducted a descriptive study to assess the influence of Hb F on clinical events and hematological variables in patients with sickle cell anemia. Methods: 151 patients with sickle cell anemia with a st...
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ورودعنوان ژورنال:
- The Journal of clinical investigation
دوره 104 7 شماره
صفحات -
تاریخ انتشار 1999